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Biol. 11: 185– 190. Hajdu-Cronin, Y. , W. J. Chen, G. Patikoglou, M. R. Koelle and P. W. Sternberg, 1999 Antagonism between Go␣ and Gq␣ in Caenorhabditis elegans : The RGS protein EAT-16 is necessary for Go␣ signaling and regulates Gq␣ activity. Genes Dev. 13: 1780– 1793. , and P. W. Sternberg, 1991 Analysis of dominant-negative mutations of the Caenorhabditis elegans let-60 ras gene. Genes Dev. 5: 2188–2198. , and C. Kenyon, 1999 Signals from the reproductive system regulate the lifespan of C.

Simpson, O. C. Grace, A. A. , 2000 Characterisation of human adenylyl cyclase IX reveals inhibition by Ca(2ϩ)/calcineurin and differential mRNA polyadenylation. J. Neurochem. 75: 1358–1367. , T. Niacaris, K. Steger, L. Avery and J. H. Thomas, 2001 eat-11 encodes GPB-2, a G␤5 ortholog that interacts with Go␣ and Gq␣ to regulate C. elegans behavior. Curr. Biol. 11: 288– 293. , D. A. Elkes and J. M. Kaplan, 1995 Modulation of serotonin-controlled behaviors by Go in Caenorhabditis elegans. Science 267: 1648–1651.

S. LI U , Y. M. HAJDU -C RONIN , M. I. , 1995 Participation of the protein Go in multiple aspects of behavior in C. elegans. Science 267: 1652-1655. M ILLER, K. , A. ALFONSO , M. NGUYEN , J. A. CROWELL , C. D. , 1996 A genetic selection for Caenorhabditis elegans synaptic transmission mutants. Proc Natl Acad Sci U S A 93: 12593-12598. MILLER, K. , M. D. EMERSON, J. R. MCMANUS and J. B. RAND, 2000 RIC-8 (Synembryn): a novel conserved protein that is required for Gqa signaling in the C. elegans nervous system.

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