Get Antiangiogenic Agents in Cancer Therapy (Cancer Drug PDF

By Beverly A. Teicher

ISBN-10: 0896036413

ISBN-13: 9780896036413

ISBN-10: 1592594530

ISBN-13: 9781592594535

Beverly Teicher and a panel of exotic investigators survey the state of the art of antiangiogenesis examine from the lab bench to scientific trials. well timed and authoritative, the participants summarize our present realizing of tumor development and its dependence on vascular improvement, in addition to the current prestige of antiangiogenic brokers in preclinical and medical improvement. furthermore, the e-book additionally examines what's recognized in regards to the mechanisms in which those healing brokers intervene with tumor vasculature and grapples with the matter of building standards through which to evaluate their scientific efficacy. Antiangiogenic brokers in melanoma treatment deals a distinct state-of-the-art compendium of antiangiogenic examine, taking inventory of what has been complete , the place the experimental therapeutics of antiangiogenic brokers goes, and the continued evolution in their function in melanoma remedy and novel drug improvement.

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Extra info for Antiangiogenic Agents in Cancer Therapy (Cancer Drug Discovery and Development)

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And Bicher, H. I. (1981) Heterogeneous oxygen partial pressure and pH distribution in C3H mouse mammary adenocarcinoma. Cancer Res. 41, 2008–2013. 44. , and Vaupel, P. (1990) Tumor tissue oxygenation as evaluated by computerized-pO2-histography. Int. J. Radiat. Oncol. Biol. Phys. 19, 953–961. 45. Horsman, M. , Hansen, P. , and Overgaard, J. (1989) Radiosensitization by nicotinamide in tumors and normal tissues: the importance of tissue oxygenation status. Int. J. Radiat. Oncol. Biol. Phys. 16, 1273–1276.

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14, 263–277. 40. , et al. (1997) Expression of the angiogenic factors VEGF, acidic and basic FGF, TGF `-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis. Cancer Res. 57, 963–969. 41. Thomlinson, R. H. and Gray, L. H. (1955) Histological structure of some human lung cancers and the possible implications for radiotherapy. Br. J. Cancer 9, 539–549. 42. Overgaard, J. and Horsman, M. R. (1996) Modification of hypoxia-induced radioresistance in tumors by the use of oxygen and sensitizers.

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Antiangiogenic Agents in Cancer Therapy (Cancer Drug Discovery and Development) by Beverly A. Teicher


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