Download e-book for iPad: Anticoagulation and Hemostasis in Neurosurgery by Christopher M. Loftus

By Christopher M. Loftus

ISBN-10: 3319273256

ISBN-13: 9783319273259

ISBN-10: 3319273272

ISBN-13: 9783319273273

​This publication is an updated reference on all facets of anticoagulation and hemostasis in neurosurgery. After a gap part on uncomplicated rules and drug periods in present use, specific attention is given to coagulation matters proper to all sufferers, not only neurosurgical ones. The assurance contains, for instance, deep vein thrombosis, pulmonary embolism, and disseminated intravascular coagulation. quite a few very important concerns particular to neurosurgical perform are then addressed, and a precis of present instructions and top practices is supplied. via bringing jointly the most recent wisdom from around the self-discipline, this ebook will function a valid foundation for trained choice making in surgical perform. will probably be of day-by-day worth for neurosurgeons and trainees all over the world and also will be of curiosity to emergency room physicians, surgeons often, severe care physicians, neurologists, and health center drugs specialists.

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Blood is collected into a syringe and transferred to a blue-top collection tube. Less commonly other anticoagulants are used for hemostasis specimens, and certain tests require further handling precautions. The laboratory will provide guidance for proper collection to assure that validated specimens are used. Hemostasis Specimen Management The citrated specimen once collected is maintained as well-mixed, whole blood, sealed and at 18–24 °C. Storage at 1–6 °C activates factor VII, destroys platelet activity and causes cryoprecipitation of large VWF multimers.

New York, NY: Springer Science + Business Media; 2007. p. 143–66. 7. com. Accessed 4 Mar 2015. 8. org. Accessed 4 Mar 2015. 9. com (Dorothy Adcock, MD). Accessed 4 Mar 2015. 10. com (Kandice Kottke-Marchant, MD, PhD). Accessed 4 Mar 2015. 11. org (Elizabeth M. Van Cott, MD and Michael Laposata, MD, PhD). Accessed 4 Mar 2015. 3 Current Anticoagulation Drugs and Mechanisms of Action Tarik F. Ibrahim, Sean Maxwell, and Omer Iqbal Introduction The era of advanced medical treatment has resulted in an increasingly elderly population that is faced with multiple, complex disease processes.

In emergent situations, dialysis can be used to remove DTIs [49]. Other agents that have been considered are antifibrinolytic agents (tranexamic acid, ε-aminocaproic acid). Patients who have taken a DTI dose in the 1–2 h prior to presentation can also be given oral activated charcoal to remove the drug. Factor Xa Inhibitors Drugs: Indirect—Fondaparinux (Arixtra) (Fig. 7) Direct—Rivaroxaban (Xarelto), Apixaban (Eliquis), Edoxaban (Savaysa) Mechanism of Action Factor Xa inhibitors are another class of TSOACs that affect the common coagulation pathway.

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Anticoagulation and Hemostasis in Neurosurgery by Christopher M. Loftus

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